Casein (Bovine) polyclonal, anti-human, mouse, rat, bovine

Protein Family: Transporters

Pathway and Disease: Amino Acid Metabolism

Description:
Beta-casein in involved in micelle formation. Caseins are the predominant milk proteins in most mammals. Casein, a 209 aa protein, yields three short peptides after cleavage: casoparan (5 aa), antioxidant peptide (8 aa) and casohypotensin (8 aa). Casoparan acts as a macrophage activator and a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide and a strong competitive inhibitor of endo-oligopeptidase A. The antioxidant peptide has antioxidant activity. Bovine milk casein is mainly found as alpha-s1, alpha-s2, beta, and kappa subunits ranging from 19-25 kDa.

Alternate Names: Casein, Beta-casein, CSN2, casoparan, antioxidant peptide, casohypotensin

Application Notes: This antibody binds to the main subunits of casein: alpha, beta and kappa. E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P02666

Antigen: Cow milk casein

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Paquette SG et al. 2015. Division of Experimental Therapeutics, Toronto General Hospital Research Institute. Oct 8
11(10). PMID: 26448646 .
[2]Ao J et al. 2015. Int J Mol Sci. 16: 29936-29947. PMID# 26694361.