Casein Kinase Iγ1/2/3 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,

Synonyms: CSNK1G1, Casein kinase I isoform gamma-1, CKI-gamma 1, CSNK1G2, CK1G2, Casein kinase I isoform gamma-2, CKI-gamma 2, CSNK1G3, Casein kinase I isoform gamma-3, CKI-gamma 3

Gene Name: CSNK1G1/CSNK1G2/CSNK1G3

Gene ID: 53944/1455/1456

SwissProt ID: Q9HCP0/P78368/Q9Y6M4

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.