CASP1 polyclonal, anti-mouse

Background:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Synonyms: ICE, IL1BC, P45, Caspase 1, IL1B convertase

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CASP1

Gene Symbol: CASP1

Gene ID: 834

Swiss prot: P29466

Calculated MW: 45kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.