CASP14 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6846b
Background:
CASP14 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo.
Other Names:
Caspase-14, CASP-14, 3422-, Caspase-14 subunit p19, Caspase-14 subunit p10, CASP14
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6846b was selected from the C-term region of human CASP14. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CASP14
Gene ID: 23581
Primary Accession: P31944
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CASP14 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo.
Other Names:
Caspase-14, CASP-14, 3422-, Caspase-14 subunit p19, Caspase-14 subunit p10, CASP14
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6846b was selected from the C-term region of human CASP14. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CASP14
Gene ID: 23581
Primary Accession: P31944
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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