CASP2 polyclonal, anti-human, mouse

Background:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms: CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57

Cellular Location: Cytosol Nucleus Mitochondrion

Immunogen:
Recombinant protein of human CASP2

Gene Symbol: CASP2

Gene ID: 835

Swiss prot: P42575

Calculated MW: 51kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.