CASP6 Antibody (N-term) Blocking peptide

CASP6 Antibody (N-term) Blocking peptide

€363.00
In stock
SKU
AC-BP13835a
Catalog Number: AC-BP13835a
Size: 500 µg
Datasheet
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Background:
This gene encodes a protein which is a member of thecysteine-aspartic acid protease (caspase) family. Sequentialactivation of caspases plays a central role in the execution-phaseof cell apoptosis. Caspases exist as inactive proenzymes whichundergo proteolytic processing at conserved aspartic residues toproduce two subunits, large and small, that dimerize to form theactive enzyme. This protein is processed by caspases 7, 8 and 10,and is thought to function as a downstream enzyme in the caspaseactivation cascade. Alternative splicing of this gene results intwo transcript variants that encode different isoforms. [providedby RefSeq].

Other Names:
Caspase-6, CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13835a was selected from the N-term region of CASP6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: CASP6 (HGNC:1507)

Gene ID: 839
Primary Accession: P55212
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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