CASP6 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP13835a
Catalog Number: AC-AP13835a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33636
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33636
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq].
Other Names:
Caspase-6, CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2
Target/Specificity:
This CASP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human CASP6.
Antigen Region:
17-45
Antigen Type: Synthetic Peptide
Gene Name: CASP6 (HGNC:1507)
Gene ID: 839
Primary Accession: P55212
NCBI Accession: NP_001217.2;NP_116787.1
Other Accession: NP_116787.1;NP_001217.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq].
Other Names:
Caspase-6, CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2
Target/Specificity:
This CASP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human CASP6.
Antigen Region:
17-45
Antigen Type: Synthetic Peptide
Gene Name: CASP6 (HGNC:1507)
Gene ID: 839
Primary Accession: P55212
NCBI Accession: NP_001217.2;NP_116787.1
Other Accession: NP_116787.1;NP_001217.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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