CASP7 Polyclonal Antibody

Background:
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.

Research Area: Cancer, Cell Biology, Metabolism

Synonyms:
Apoptotic protease Mch-3, Apoptotic protease MCH3, CASP-7, CASP7, CASP7, Caspase 7, Caspase 7 apoptosis related cysteine peptidase, Caspase-7 subunit p11, Caspase7, CMH 1, CMH-1, CMH1, ICE LAP3, ICE-LAP3, ICE-like apoptotic protease 3, LICE2, MCH3

Immunogen: Synthesized peptide derived from the N-terminal region of human Caspase-7.

Swissprot: P55210

Calculated MW: 34 kDa
Observed MW: 35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ICC 1:200-1:1000, ELISA 1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-8512/sc-22179/sc-8510/sc-8511/sc-33773