Casp8 polyclonal, anti-human, mouse, rat

Background:
This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Synonyms: CASP-8, FLICE, MACH, Mch5

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of mouse Casp8

Gene Symbol: Casp8

Gene ID: 12370

Swiss prot: O89110

Calculated MW: 55 kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.