CASP8AP2 polyclonal, anti-human, mouse

Background:
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Synonyms: CED-4, FLASH, RIP25

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human CASP8AP2

Gene Symbol: CASP8AP2

Gene ID: 9994

Swiss prot: Q9UKL3

Calculated MW: 223kDa

Recommended dilution:
WB 1:200-1000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.