CASP9 antibody (clone 3B8-4G2), anti-human
€435.00
In stock
SKU
AC-AT1404a
Catalog Number: AC-AT1404a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT1404a">Request Information
Background:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.
Other Names:
Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6
Antigen Type:
Recombinant Protein
Gene Name: CASP9
Gene ID: 842
NCBI Accession: NP_001220.2;NP_001264983.1;NP_127463.2
Primary Accession: P55211
Other Accession: BC002452
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.
Other Names:
Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6
Antigen Type:
Recombinant Protein
Gene Name: CASP9
Gene ID: 842
NCBI Accession: NP_001220.2;NP_001264983.1;NP_127463.2
Primary Accession: P55211
Other Accession: BC002452
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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