Casp9 polyclonal, anti-human

Background:
Caspase 9, apoptosis-related cysteine protease (CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Caspase 9 is processed by APAF1; this step is thought to be one of the earliest in the caspase activation cascade. 10380-1-AP can recognize the pre- and cleaved- caspase 9.

Synonyms: CT30, DP4, HCA661, E2F like, Cancer/testis antigen 30

Cellular Location: Nucleus Cytoplasm

Immunogen:
Recombinant protein of human Casp9

Gene Symbol: Casp9

Gene ID: 842

Swiss prot: p55211

Calculated MW: 47kDa

Recommended dilution:
WB 1:5000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.