CASP9 polyclonal, anti-human, mouse

Background:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.

Synonyms: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human CASP9

Gene Symbol: CASP9

Gene ID: 842

Swiss prot: P55211

Calculated MW: 46kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-300,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.