Caspase-1 polyclonal, anti-human, mouse, rat antibody
€340.00
In stock
SKU
AC-ABV10012-100
Catalog Number: AC-ABV10012-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IF, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IF, IP
Datasheet
Request Information
Background:
Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1β and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.
Other Names:
CASP1, IL1BCE, P45, Interleukin-1 beta convertase, IL-1BC, IL1BC, p45, IL1B-convertase, CASP-1, ICE
Primary Accession: P29466
Other Accession: NP_150636
Gene Name: CASP1
Gene ID: 834
Concentration (mg/ml): 0.2 mg/ml
Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1β and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.
Other Names:
CASP1, IL1BCE, P45, Interleukin-1 beta convertase, IL-1BC, IL1BC, p45, IL1B-convertase, CASP-1, ICE
Primary Accession: P29466
Other Accession: NP_150636
Gene Name: CASP1
Gene ID: 834
Concentration (mg/ml): 0.2 mg/ml
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