Caspase-2 polyclonal, anti-human, mouse, rat antibody

Caspase-2 polyclonal, anti-human, mouse, rat antibody

€285.00
In stock
SKU
AC-ABV10019-100
Catalog Number: AC-ABV10019-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet

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Background:
Caspases play a key role in apoptosis. Similar as other caspases, caspase-2 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Caspase-2 mRNA is alternatively spliced. The larger mRNA species encoding a product of 435 amino acids is known as ICH-1L. The smaller mRNA species encoding a protein of 312 amino acids is named ICH-1S. Over expression of ICH-1L induces apoptosis, while over expression of ICH-1S suppresses Rat-1 cell death induced by serum deprivation.

Other Names:
CASP-2, NEDD-2, NEDD2, ICH1, ICH-1L/1S, ICH-1L, EC 3.4.22.55

Primary Accession: P29594

Other Accession: D28492

Gene Name: Casp2

Gene ID: 12366

Concentration (mg/ml): 0.2 mg/ml
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