Caspase 2 Rabbit polyclonal antibody, anti-human, mouse, rat
€0.00
In stock
SKU
BT-AP06906
Catalog Number: BT-AP06906
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): WB, ELISA
Datasheet
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Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): WB, ELISA
Datasheet
Request Information
Background:
alternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.|Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.|PTM:The mature protease can process its own propeptide| but not that of other caspases.|Belongs to the peptidase C14A family.|Contains 1 CARD domain.|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.|tissue specificity:Expressed at higher levels in the embryonic lung| liver and kidney than in the heart and brain. In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle.|
Research Area: Cancer, Cell biology, Metabolism
Synonyms: Caspase 2 , p13, Cleaved-Gly334, Caspase-2, CASP-2, EC 3.4.22.55, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1, Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12,
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
alternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.|Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.|PTM:The mature protease can process its own propeptide| but not that of other caspases.|Belongs to the peptidase C14A family.|Contains 1 CARD domain.|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.|tissue specificity:Expressed at higher levels in the embryonic lung| liver and kidney than in the heart and brain. In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle.|
Research Area: Cancer, Cell biology, Metabolism
Synonyms: Caspase 2 , p13, Cleaved-Gly334, Caspase-2, CASP-2, EC 3.4.22.55, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1, Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12,
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
| Is Featured? | No |
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