14-3-3 σ polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP68195
Background:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Other Names:
SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin
Antigen Type: synthetic peptide
Antigen Type: SFN
Gene ID: 2810
Primary Accession: P31947
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Other Names:
SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin
Antigen Type: synthetic peptide
Antigen Type: SFN
Gene ID: 2810
Primary Accession: P31947
| Is Featured? | No |
|---|
Write Your Own Review