Caspase-4 polyclonal, anti-human, mouse, rat antibody
€275.00
In stock
SKU
AC-ABV10020-100
Catalog Number: AC-ABV10020-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as other autoimmune diseases. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-4 is also known as Ich-2, TX, and ICErel-II and can proteolytically processed by granzyme B. Over expression of caspase-4 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2.
Other Names:
CASP-4, ICH-2 protease, TX protease, ICH2
Primary Accession: P49662
Gene Name: CASP4
Gene ID: 837
Concentration (mg/ml): 0.2 mg/ml
Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as other autoimmune diseases. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-4 is also known as Ich-2, TX, and ICErel-II and can proteolytically processed by granzyme B. Over expression of caspase-4 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2.
Other Names:
CASP-4, ICH-2 protease, TX protease, ICH2
Primary Accession: P49662
Gene Name: CASP4
Gene ID: 837
Concentration (mg/ml): 0.2 mg/ml
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