Caspase-7 (P11) polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CASP7, Caspase-7, apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the caspase(cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta(PRKCD)-dependent pathway.

Description:
Rabbit IgG polyclonal antibody for Caspase-7 (CASP7) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Apoptosis related cysteine peptidase antibody, Apoptosis Related Cysteine Protease antibody, Apoptotic protease Mch-3 antibody, Apoptotic Protease MCH3 antibody, CASP 7 antibody, CASP-7 antibody, CASP7 antibody, Caspase-7 subunit p11 antibody, Caspase7 antibody, CMH 1 antibody, CMH-1 antibody, CMH1 antibody, ICE LAP3 antibody, ICE like Apoptotic Protease 3 antibody, ICE-LAP3 antibody, ICE-like apoptotic protease 3 antibody, MCH3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Caspase-7(P11)(237-255aa RGSWFVQALCSILEEHGKD), different from the related mouse and rat sequences by two amino acids.A synthetic peptide corresponding to a sequence in the middle region of human Caspase-7(P11)(237-255aa RGSWFVQALCSILEEHGKD), different from the related mouse and rat sequences by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.