Caspase-9 polyclonal, anti-human

Protein Family: Peptidases, Enzymes

Pathway and Disease: Signal Transduction, Cell Growth and Death, Cancers

Description:
Caspase-9 is known to be involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Caspase-9 proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Alternate Names: Caspase-9, CASP-9, ICE-like apoptotic protease 6, ICE-LAP6, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, CASP9, MCH6

Application Notes: E: 1:20,000-1:80,000; WB: 1:200-1:1,000; IF: 1:100-1:500

Accession No.: P55211

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human caspase-9.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by peptide-affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.