CASR polyclonal (Center), anti-mouse
€0.00
In stock
SKU
AC-AP20157c
Catalog Number: AC-AP20157c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41198
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41198
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq].
Other Names:
Extracellular calcium-sensing receptor, CaSR, Parathyroid cell calcium-sensing receptor 1, PCaR1, CASR, GPRC2A, PCAR1
Target/Specificity:
This CASR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-287 amino acids from the Central region of human CASR.
Antigen Region:
260-287
Antigen Type: Synthetic Peptide
Gene Name: CASR (HGNC:1514)
Gene ID: 846
Primary Accession: P41180
NCBI Accession: NP_000379.2;NP_001171536.1
Other Accession: P48442; Q9QY96; P35384; NP_000379.2; O62714
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq].
Other Names:
Extracellular calcium-sensing receptor, CaSR, Parathyroid cell calcium-sensing receptor 1, PCaR1, CASR, GPRC2A, PCAR1
Target/Specificity:
This CASR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-287 amino acids from the Central region of human CASR.
Antigen Region:
260-287
Antigen Type: Synthetic Peptide
Gene Name: CASR (HGNC:1514)
Gene ID: 846
Primary Accession: P41180
NCBI Accession: NP_000379.2;NP_001171536.1
Other Accession: P48442; Q9QY96; P35384; NP_000379.2; O62714
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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