CAT monoclonal (Center) (Ascites), anti-human, mouse
€470.00
In stock
SKU
AC-AM2118a
Catalog Number: AC-AM2118a
Size: 100 µl
Isotype: mouse IgG2a
Clone Name: 626CT4.3.8
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgG2a
Clone Name: 626CT4.3.8
Applications: WB
Datasheet
Request Information
Background:
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Other Names:
Catalase, CAT
Target/Specificity:
This CAT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CAT.
Antigen Region:
152-180
Antigen Type: Synthetic Peptide
Gene Name: CAT
Gene ID: 847
Primary Accession: P04040
NCBI Accession: NP_001743.1
Other Accession: P04762; O62839; P24270; Q9PT92; P00432; NP_001743.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Other Names:
Catalase, CAT
Target/Specificity:
This CAT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CAT.
Antigen Region:
152-180
Antigen Type: Synthetic Peptide
Gene Name: CAT
Gene ID: 847
Primary Accession: P04040
NCBI Accession: NP_001743.1
Other Accession: P04762; O62839; P24270; Q9PT92; P00432; NP_001743.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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