CAT Polyclonal Antibody

Background:
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
CAT, catalase, MGC138422, MGC138424

Immunogen: Recombinant fusion protein of human CAT (NP_001743.1).

Swissprot: P04040
Gene ID: 847

Calculated MW: 59 kDa
Observed MW: 59 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:3000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.