Cathepsin B polyclonal, anti-human antibody
€295.00
In stock
SKU
AC-ABV10156-100
Catalog Number: AC-ABV10156-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, FC
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, FC
Datasheet
Request Information
Background:
Cathepsin B is a normal lysosomal cysteine proteinase that is expressed in all cells. It is synthesized as an inactive 43 kDa pro-enzyme which, by removal of a 62 amino acid propeptide, is activated to the single-chain form of 31 kDa or the two-chain form (25 and 5 kDa subunits). Matured cathepsin B is normally localized in the lysosomes where it functions in protein turnover. Cathepsin B is also shown capable of degrading extracellular matrix proteins. Elevated levels of cathepsin B correlate with malignancy s µggesting that this enzyme may be a useful prognostic marker for several types of human cancers.
Other Names:
CTSB, CPSB, APPS, EC 3.4.22.1
Primary Accession: P07858
Gene Name: CTSB
Gene ID: 1508
Concentration (mg/ml): 0.2 mg/ml
Cathepsin B is a normal lysosomal cysteine proteinase that is expressed in all cells. It is synthesized as an inactive 43 kDa pro-enzyme which, by removal of a 62 amino acid propeptide, is activated to the single-chain form of 31 kDa or the two-chain form (25 and 5 kDa subunits). Matured cathepsin B is normally localized in the lysosomes where it functions in protein turnover. Cathepsin B is also shown capable of degrading extracellular matrix proteins. Elevated levels of cathepsin B correlate with malignancy s µggesting that this enzyme may be a useful prognostic marker for several types of human cancers.
Other Names:
CTSB, CPSB, APPS, EC 3.4.22.1
Primary Accession: P07858
Gene Name: CTSB
Gene ID: 1508
Concentration (mg/ml): 0.2 mg/ml
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