Cathepsin B polyclonal, anti-human

Background:
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.

Alternative Name:
APPS, CTSB, Amyloid precursor protein secretase, APP secretase, APPS, CATB, Cathepsin B heavy chain, Cathepsin B1, CathepsinB, CPSB, CTSB, cysteine protease, OTTHUMP00000116009, OTTHUMP00000229510, OTTHUMP00000229511, OTTHUMP00000229512, OTTHUMP00000229514, OTTHUMP00000229515, OTTHUMP00000229516, Preprocathepsin B,

Application Dilution:
WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200

Specificity: Cathepsin B polyclonal antibody detects endogenous levels of Cathepsin B protein.

Immunogen:
recombinant protein

MW: 38 kDa

Swiss-Prot: P07858(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.