Cathepsin K polyclonal, anti-human

Background:
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

Other Names:
Cathepsin K, 3.4.22.38, Cathepsin O, Cathepsin O2, Cathepsin X, CTSK, CTSO, CTSO2

Antigen Types:
Synthetic Peptide

Gene Name:
CTSK
Gene ID:
1513
Primary Accession: P43235
Other Accession: NP_000387;1513;