Cathepsin L polyclonal, anti-human antibody
€285.00
In stock
SKU
AC-ABV10158-100
Catalog Number: AC-ABV10158-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Background:
Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins s µggests that it may play a role in invasion and metastasis and could be a useful prognostic indicator for cancer.
Other Names:
CTSL, CATL, CTSL1, MEP, EC 3.4.22.15
Primary Accession: P07711
Gene Name: CTSL
Gene ID: 1514
Concentration (mg/ml): 0.2 mg/ml
Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins s µggests that it may play a role in invasion and metastasis and could be a useful prognostic indicator for cancer.
Other Names:
CTSL, CATL, CTSL1, MEP, EC 3.4.22.15
Primary Accession: P07711
Gene Name: CTSL
Gene ID: 1514
Concentration (mg/ml): 0.2 mg/ml
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