Cathepsin L Polyclonal Antibody

Background:
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
cathepsin L, 1 b, Cathepsin L1, Cathepsin L1 light chain, CathepsinL, CATL, CATL1, cb15, CTSL, CTSL1, ctsl1b, FLJ31037, hgg1, Major excreted protein, MEP, MGC123162, wu:fb30g09

Immunogen: Recombinant protein of human CTSL

Swissprot: P07711
Gene Accession: BC012612

Calculated MW: 38 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6500/sc-6498/sc-10778/sc-25537