CaV1.3 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CACNA1D is also known as PASNA, SANDD or Cav1.3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.

Description:
Rabbit IgG polyclonal antibody for Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
alpha-1 polypeptide antibody, CAC1D_HUMAN antibody, CACH3 antibody, CACN4 antibody, CACNA 1D antibody, CACNA1D antibody, CACNL1A2 antibody, Calcium channel antibody, Calcium channel L type alpha 1 polypeptide isoform 2 antibody, Calcium channel neuroendocrine/brain type alpha 1 subunit antibody, Calcium channel voltage dependent L type alpha 1 antibody, Calcium channel voltage dependent L type alpha 1D subunit antibody, Cav1.3 antibody, CCHL1A2 antibody, L type antibody, PASNA antibody, SANDD antibody, Voltage dependent L type calcium channel subunit alpha 1D antibody, Voltage gated calcium channel alpha 1 subunit antibody, Voltage gated calcium channel alpha subunit Cav1.3 antibody, Voltage gated calcium channel subunit alpha Cav1.3 antibody, Voltage-dependent L-type calcium channel subunit alpha-1D antibody, Voltage-gated calcium channel subunit alpha Cav1.3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CaV1.3 recombinant protein (Position: M1-I180). Human CaV1.3 shares 99% and 98%amino acid (aa) sequence identity with mouse and rat CaV1.3, respectively.E.coli-derived human CaV1.3 recombinant protein (Position: M1-I180). Human CaV1.3 shares 99% and 98%amino acid (aa) sequence identity with mouse and rat CaV1.3, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.