CAV3 Polyclonal Antibody

Background:
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Research Area: Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction, Tags and Cell Markers

Synonyms:
CAV3, CAV3, Caveolin 3, Caveolin-3, LGMD1C, LQT9, M-caveolin, MGC126100, MGC126101, MGC126129, OTTHUMP00000115603, OTTHUMP00000207105, VIP 21, VIP21

Immunogen: Synthetic peptide of human CAV3

Swissprot: P56539
Gene Accession: NP_001225

Calculated MW: 17 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7665/sc-5437/sc-30753/sc-30752/sc-55518/sc-28828