CAV3 Polyclonal Antibody

Background:
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Research Area: Cancer, Cardiovascular, Metabolism, Developmental Biology, Signal Transduction, Tags and Cell Markers

Synonyms:
CAV3, LGMD1C, LQT9, VIP-21, VIP21

Immunogen: Recombinant fusion protein of human CAV3 (NP_001225.1).

Swissprot: P56539
Gene ID: 859

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.