Caveolin-1 (clone D16), anti-human, mouse, rat

Background:
Caveolins are a family ofHYPERLINK "http://en.wikipedia.org/wiki/Integral_membrane_protein" \o "Integral membrane protein"integral membrane proteinswhich are the principal components ofHYPERLINK "http://en.wikipedia.org/wiki/Caveolae" \o "Caveolae"caveolaemembranes and involved in receptor-independentHYPERLINK "http://en.wikipedia.org/wiki/Endocytosis" \o "Endocytosis"endocytosis.HYPERLINK "http://en.wikipedia.org/wiki/Caveolin" \l "cite_note-pmid8567687-0"[1], they are found in the majority of adherent, mammalian cells, and played an important role during the development of atherosclerosis.HYPERLINK "http://en.wikipedia.org/wiki/Caveolin" \l "cite_note-pmid15768830-4"[2]Caveolin 1(CAV1) is a member of Caveolin gene family, and most prominently expressed inHYPERLINK "http://en.wikipedia.org/wiki/Endothelium" \o "Endothelium"endothelial,HYPERLINK "http://en.wikipedia.org/wiki/Fibrous_connective_tissue" \o "Fibrous connective tissue"fibrousandHYPERLINK "http://en.wikipedia.org/wiki/Adipose_tissue" \o "Adipose tissue"adiposetissue. It contains 3 exons spanning about 22 kD. It can link the integrin alpha subunit to the tyrosine kinase as a membrane adaptor[3].

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of mouse Caveolin-1.

Recommended Application:
Western Blot, WB(1:100-200); Immunohistochemistry, IHC-P(1:100); Immunocytochemistry, ICC(1:100)

Product Form: Liquid

Purification: Protein A purified

Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.

Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.