Caveolin 1 rabbit polyclonal, anti-human

Backgroud: Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Synonyms: CAV1, CAV, Caveolin-1

Gene Name: CAV1

Gene ID: 857

SwissProt ID: Q03135

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.