Caveolin-2 polyclonal, anti-human, mouse

Quantity: 100 µg

Background:
Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. It is mapped to 7q31.1-q31.2. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both of them are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury.

Description:
Rabbit IgG polyclonal antibody for Caveolin-2 (CAV2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse.

Synonyms:
CAV antibody, CAV2 antibody, CAV2_HUMAN antibody, Caveolae protein 20 kD antibody, Caveolae protein 20kD antibody, Caveolin 2 isoform a and b antibody, Caveolin 2 isoform c antibody, Caveolin-2 antibody, MGC12294 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Caveolin-2 recombinant protein (Position: M1-D162). Human Caveolin-2 shares 90% and 89% amino acid (aa) sequences identity with mouse and rat Caveolin-2, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.