Caveolin-2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Caveolin-1 and caveolin-2 are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of CAV1 and CAV2 are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.

Description:
Rabbit IgG polyclonal antibody for Caveolin-2 (CAV2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
CAV antibody, CAV2 antibody, CAV2_HUMAN antibody, Caveolae protein 20 kD antibody, Caveolin 2 antibody, Caveolin 2 isoform a and b antibody, Caveolin-2 antibody, MGC12294 antibody, OTTHUMP00000025032 antibody, OTTHUMP00000195982 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Caveolin-2(1-17aa MGLETEKADVQLFMDDD), different from the related rat and mouse sequences by one amino acid.A synthetic peptide corresponding to a sequence at the N-terminus of human Caveolin-2(1-17aa MGLETEKADVQLFMDDD), different from the related rat and mouse sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.