CBFA2T3 polyclonal, anti-human
€388.00
In stock
SKU
BS72475
Background:
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Alternative Name:
ETO2,MTG16,MTGR2,RUNX1T3,ZMYND4
Application Dilution: WB: 1:500 - 1:2000
Specificity: CBFA2T3 polyclonal antibody detects endogenous levels of CBFA2T3 protein.
Immunogen:
Recombinant protein of human CBFA2T3
MW: ~ 60 kDa
Swis Prot.: O75081
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Alternative Name:
ETO2,MTG16,MTGR2,RUNX1T3,ZMYND4
Application Dilution: WB: 1:500 - 1:2000
Specificity: CBFA2T3 polyclonal antibody detects endogenous levels of CBFA2T3 protein.
Immunogen:
Recombinant protein of human CBFA2T3
MW: ~ 60 kDa
Swis Prot.: O75081
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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