CBS polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Cystathionine-β-synthase, also known as CBS, is an enzyme that in humans is encoded by the CBS gene. It is mapped to 21q22.3 and contains 23 exons, ranging in size from 42 to 299 bp. CBS catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine. It uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria.

Description:
Rabbit IgG polyclonal antibody for Cystathionine beta-synthase (CBS) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
AI047524 antibody, AI303044 antibody, Beta thionase antibody, Beta-thionase antibody, Cbs antibody, Cbs cystathionine beta-synthase antibody, CBS_HUMAN antibody, Cystathionine beta synthase antibody, Cystathionine beta-synthase antibody, EC 4.2.1.22 antibody, HIP 4 antibody, HIP4 antibody, Methylcysteine synthase antibody, MGC18856 antibody, MGC18895 antibody, MGC37300 antibody, OTTHUMP00000109416 antibody, OTTHUMP00000109418 antibody, Serine sulfhydrase antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CBS recombinant protein (Position: A331-K551). Human CBS shares 83% amino acid (aa) sequence identity with both mouse and rat CBS.E.coli-derived human CBS recombinant protein (Position: A331-K551). Human CBS shares 83% amino acid (aa) sequence identity with both mouse and rat CBS.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.