CBX1 (clone 5A3), anti-human, monkey

CBX1 (clone 5A3), anti-human, monkey

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In stock
SKU
BT-MCA3914
Catalog Number: BT-MCA3914
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human, monkey
Application(s): WB, ICC, FCM
Datasheet
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Background:
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Research Area: Epigenetics and nuclear signaling

Synonyms: CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta, CBX1

Immunogen: Purified recombinant fragment of human CBX1 expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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