CBX2 polyclonal, anti- antibody
€215.00
In stock
SKU
AC-ABV11375-50
Catalog Number: AC-ABV11375-50
Size: 50 µl
Host: Rabbit IgG
Applications: E
Datasheet
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Size: 50 µl
Host: Rabbit IgG
Applications: E
Datasheet
Request Information
Background:
CBX2 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodelling and modification of histones, it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility. CBX2 also is involved in sexual development, acting as an activator of NR5A1 expression.
Other Names:
CDCA6, M33, SRXY5
Primary Accession: Q14781
Gene Name: CBX2
Gene ID: 84733
CBX2 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodelling and modification of histones, it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility. CBX2 also is involved in sexual development, acting as an activator of NR5A1 expression.
Other Names:
CDCA6, M33, SRXY5
Primary Accession: Q14781
Gene Name: CBX2
Gene ID: 84733
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