CBX5 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13779c
Background:
This gene encodes a highly conserved nonhistone protein,which is a member of the heterochromatin protein family. Theprotein is enriched in the heterochromatin and associated withcentromeres. The protein has a single N-terminal chromodomain whichcan bind to histone proteins via methylated lysine residues, and aC-terminal chromo shadow-domain (CSD) which is responsible for thehomodimerization and interaction with a number ofchromatin-associated nonhistone proteins. The encoded product isinvolved in the formation of functional kinetochore throughinteraction with essential kinetochore proteins. The gene has apseudogene located on chromosome 3. Multiple alternatively splicedvariants, encoding the same protein, have been identified.
Other Names:
Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha, CBX5, HP1A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13779c was selected from the Center region of CBX5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CBX5
Gene ID: 23468
Primary Accession: P45973
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a highly conserved nonhistone protein,which is a member of the heterochromatin protein family. Theprotein is enriched in the heterochromatin and associated withcentromeres. The protein has a single N-terminal chromodomain whichcan bind to histone proteins via methylated lysine residues, and aC-terminal chromo shadow-domain (CSD) which is responsible for thehomodimerization and interaction with a number ofchromatin-associated nonhistone proteins. The encoded product isinvolved in the formation of functional kinetochore throughinteraction with essential kinetochore proteins. The gene has apseudogene located on chromosome 3. Multiple alternatively splicedvariants, encoding the same protein, have been identified.
Other Names:
Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha, CBX5, HP1A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13779c was selected from the Center region of CBX5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CBX5
Gene ID: 23468
Primary Accession: P45973
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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