CBX7 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP21163a
Catalog Number: AC-AP21163a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51547
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51547
Applications: WB
Datasheet
Request Information
Background:
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Other Names:
Chromobox protein homolog 7, CBX7
Target/Specificity:
This CBX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 168-201 amino acids from the C-terminal region of human CBX7.
Gene Name: CBX7
Gene ID: 23492
Primary Accession: O95931
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Other Names:
Chromobox protein homolog 7, CBX7
Target/Specificity:
This CBX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 168-201 amino acids from the C-terminal region of human CBX7.
Gene Name: CBX7
Gene ID: 23492
Primary Accession: O95931
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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