CBX8 polyclonal, anti-human

Background:
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Synonyms: CBX8, PC3, RC1, chromobox 8

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human CBX8

Gene Symbol: CBX8

Gene ID: 57332

Swiss prot: Q9HC52

Calculated MW: 43kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20°C. Avoid freeze / thaw cycles.