CCK-A Receptor polyclonal, anti-rat, mouse

Quantity: 100 µl

Background:
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.

Synonyms:
CCKAR, CCK-A, CCKRA, CCK1-R

Isotype: Rabbit Polyclonal

Immunogen:
Synthetic peptide from the C terminus of rat CCK-A receptor conjugated to BSA

Form: Serum containing 0.1% sodium azide

Specificity:
Suitable for labeling the receptors for the gastrointestinal hormone and neuropeptide CCK. Absorption with 10-100 ?g per ml diluted antiserum abolishes the staining.

Reactivity: rat, mouse

Applications: Immunohistochemistry, suitable in frozen sections

Working DIlution: 1:75 to 1: 125 using FITC

Positive Control:
Frozen sections of rat pancreas

Storage: 2-8C for immediate use, or at -20C (aliquot)