CCL17 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7736
Background:
Chemokines have been implicated in the regulation of stem/progenitor cell proliferation and movement. The C-C chemokines TARC (for thymus and activation-regulated chemokine, also designated small inducible cytokine A17) and MDC (for macrophage-derived chemokine, also designated small inducible cytokine A22 or STCP-1, for stimulated T cell chemotactic protein 1), are expressed in the thymus and spleen. C-C chemokine receptor CCR4, expressed by T helper type 2 polarized cells, is a high affinity receptor for both TARC and MDC. TARC is important in the recognition of skin vasculature by circulating T cells and in directing lymphocytes that are involved in systemic as opposed to intestinal immunity to its target tissues. MDC is involved in chronic inflammation and dendritic cell and lymphocyte homing. MDC and TARC lack suppressive activity against immature subsets of myeloid progenitors, which have been stimulated to proliferate by multiple growth factors .
Alternative Name:
A152E53, ABCD 2, ABCD2, C-C motif chemokine 17, CC chemokine TARC, CCL17, CCL17_HUMAN, Chemokine CC Motif Ligand 17, MGC138271, MGC138273, SCYA17, SCYA17, Small Inducible Cytokine A17, Small Inducible Cytokine A17 Precursor, Small Inducible Cytokine Subfamily A (Cys Cys), Small Inducible Cytokine Subfamily A (Cys Cys) Member 17, Small-inducible cytokine A17, T Cell Directed CC Chemokine, Thymus and activation regulated chemokine, Thymus and activation-regulated chemokine
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: CCL17 polyclonal antibody detects endogenous levels of CCL17 protein.
Immunogen:
Recombinant full length Human CCL17.
MW: ~ 11 kDa
Swis Prot.: Q92583
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Chemokines have been implicated in the regulation of stem/progenitor cell proliferation and movement. The C-C chemokines TARC (for thymus and activation-regulated chemokine, also designated small inducible cytokine A17) and MDC (for macrophage-derived chemokine, also designated small inducible cytokine A22 or STCP-1, for stimulated T cell chemotactic protein 1), are expressed in the thymus and spleen. C-C chemokine receptor CCR4, expressed by T helper type 2 polarized cells, is a high affinity receptor for both TARC and MDC. TARC is important in the recognition of skin vasculature by circulating T cells and in directing lymphocytes that are involved in systemic as opposed to intestinal immunity to its target tissues. MDC is involved in chronic inflammation and dendritic cell and lymphocyte homing. MDC and TARC lack suppressive activity against immature subsets of myeloid progenitors, which have been stimulated to proliferate by multiple growth factors .
Alternative Name:
A152E53, ABCD 2, ABCD2, C-C motif chemokine 17, CC chemokine TARC, CCL17, CCL17_HUMAN, Chemokine CC Motif Ligand 17, MGC138271, MGC138273, SCYA17, SCYA17, Small Inducible Cytokine A17, Small Inducible Cytokine A17 Precursor, Small Inducible Cytokine Subfamily A (Cys Cys), Small Inducible Cytokine Subfamily A (Cys Cys) Member 17, Small-inducible cytokine A17, T Cell Directed CC Chemokine, Thymus and activation regulated chemokine, Thymus and activation-regulated chemokine
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: CCL17 polyclonal antibody detects endogenous levels of CCL17 protein.
Immunogen:
Recombinant full length Human CCL17.
MW: ~ 11 kDa
Swis Prot.: Q92583
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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