CCL18 Polyclonal Antibody

Background:
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.

Research Area: Cancer, Immunology

Synonyms:
Alternative macrophage activation associated CC chemokine 1, Alternative macrophage activation-associated CC chemokine 1, AMAC-1, AMAC1, CC chemokine PARC, CCL18, CCL18(4-69), CCL18, CKb7, DC-CK1, DCCK1 , DCCK1, Dendritic cell chemokine 1, Macrophage inflammatory protein 4, MIP-4, MIP4, PARC, Pulmonary and activation regulated chemokine, Pulmonary and activation-regulated chemokine, SCYA18, Small inducible cytokine A18 , Small inducible cytokine A18, Small-inducible cytokine A18

Immunogen: Synthetic peptide of human CCL18

Swissprot: P55774
Gene Accession: NP002979

Calculated MW: 10 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.1 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.