CCL21 Polyclonal Antibody

Background:
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Research Area: Cancer, Immunology

Synonyms:
6Ckine, Beta-chemokine exodus-2, C C motif chemokine ligand 21, C-C motif chemokine 21, CCL21, CCL21, Chemokine (C-C motif) ligand 21, Chemokine CC motif ligand 21, CKb9, ECL, Efficient Chemoattractant for Lymphocytes, SCYA21, Secondary lymphoid-tissue chemokine, SLC, Small inducible cytokine A21, Small inducible cytokine subfamily A (Cys-Cys), member 21, Small-inducible cytokine A21, TCA4, UNQ784/PRO1600

Immunogen: Recombinant protein of human CCL21

Swissprot: O00585
Gene Accession: BC027918

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-5808/sc-25445