CCL22 polyclonal, anti-human, rat
€388.00
In stock
SKU
BS7709
Background:
Chemokines have been implicated in the regulation of stem/progenitor cell proliferation and movement. The C-C chemokines TARC (for thymus and activation-regulated chemokine, also designated small inducible cytokine A17) and MDC (for macrophage-derived chemokine, also designated small inducible cytokine A22 or STCP-1, for stimulated T cell chemotactic protein 1), are expressed in the thymus and spleen. C-C chemokine receptor CCR4, expressed by T helper type 2 polarized cells, is a high affinity receptor for both TARC and MDC. TARC is important in the recognition of skin vasculature by circulating T cells and in directing lymphocytes that are involved in systemic as opposed to intestinal immunity to its target tissues. MDC is involved in chronic inflammation and dendritic cell and lymphocyte homing. MDC and TARC lack suppressive activity against immature subsets of myeloid progenitors, which have been stimulated to proliferate by multiple growth factors.
Alternative Name:
ABCD 1, ABCD1, C C motif chemokine 22, CC chemokine STCP 1, CC chemokine STCP-1, ccl 22, Ccl22, CCL22_HUMAN, Chemokine (C C motif) ligand 22, DC/B CK, DCBCK, Macrophage-derived chemokine, MDC(1-69), MDC(7-69), MGC34554, SCYA22, Small inducible cytokine subfamily A (Cys Cys) member 22, Small-inducible cytokine A22, STCP 1, STCP1, Stimulated T cell chemotactic protein 1, Stimulated T-cell chemotactic protein 1,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: CCL22 polyclonal antibody detects endogenous levels of CCL22 protein.
Immunogen:
Recombinant full length Human CCL22.
MW: ~ 10 kDa
Swis Prot.: O00626
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Chemokines have been implicated in the regulation of stem/progenitor cell proliferation and movement. The C-C chemokines TARC (for thymus and activation-regulated chemokine, also designated small inducible cytokine A17) and MDC (for macrophage-derived chemokine, also designated small inducible cytokine A22 or STCP-1, for stimulated T cell chemotactic protein 1), are expressed in the thymus and spleen. C-C chemokine receptor CCR4, expressed by T helper type 2 polarized cells, is a high affinity receptor for both TARC and MDC. TARC is important in the recognition of skin vasculature by circulating T cells and in directing lymphocytes that are involved in systemic as opposed to intestinal immunity to its target tissues. MDC is involved in chronic inflammation and dendritic cell and lymphocyte homing. MDC and TARC lack suppressive activity against immature subsets of myeloid progenitors, which have been stimulated to proliferate by multiple growth factors.
Alternative Name:
ABCD 1, ABCD1, C C motif chemokine 22, CC chemokine STCP 1, CC chemokine STCP-1, ccl 22, Ccl22, CCL22_HUMAN, Chemokine (C C motif) ligand 22, DC/B CK, DCBCK, Macrophage-derived chemokine, MDC(1-69), MDC(7-69), MGC34554, SCYA22, Small inducible cytokine subfamily A (Cys Cys) member 22, Small-inducible cytokine A22, STCP 1, STCP1, Stimulated T cell chemotactic protein 1, Stimulated T-cell chemotactic protein 1,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: CCL22 polyclonal antibody detects endogenous levels of CCL22 protein.
Immunogen:
Recombinant full length Human CCL22.
MW: ~ 10 kDa
Swis Prot.: O00626
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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