CCL4 polyclonal, anti-human

Quantity: 100 µg

Background:
Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. And it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines(11, 14).

Description:
Rabbit IgG polyclonal antibody for C-C motif chemokine 4 (CCL4) detection. Tested with WB, ELISA in Human.

Synonyms:
MIP 1 beta antibody, Secreted protein G 26 antibody, ACT 2 antibody, ACT-2 antibody, ACT2 antibody, AT744.1 antibody, AT744.2 antibody, C C motif chemokine 4 antibody, C C motif chemokine 4 like antibody, CC chemokine ligand 4 antibody, CC chemokine ligand 4L1d2 antibody, CC chemokine ligand 4L2 antibody, CCL4 antibody, CCL4_HUMAN antibody, ccl4l 1 antibody, CCL4L antibody, CCL4L1 antibody, Chemokine (C C motif) ligand 4 antibody, Chemokine (C C motif) ligand 4 like 1 antibody, Chemokine (C C motif) ligand 4 like 1, telomeric antibody, Chemokine (C C motif) ligand 4 like 2 antibody, Chemokine CC Motif Ligand 4 antibody, G 26 antibody, G 26 T lymphocyte secreted protein antibody, G-26 T-lymphocyte-secreted protein antibody, HC21 antibody, LAG 1 antibody, LAG-1 antibody, LAG1 antibody, Lymphocyte activation gene 1 antibody, Lymphocyte activation gene 1 protein antibody, Macrophage inflammatory protein 1 beta antibody, Macrophage inflammatory protein 1-beta antibody, Macrophage inflammatory protein 1b2 antibody, MGC104418 antibody, MGC126025 antibody, MGC126026 antibody, MIP-1-beta antibody, MIP-1-beta(1-69) antibody, MIP-1-beta(3-69) antibody, MIP1 beta antibody, MIP1B antibody, MIP1B1 antibody, Monocyte adherence induced protein 5 alpha antibody, PAT 744 antibody, Protein H400 antibody, SCYA2 antibody, SCYA4 antibody, SCYA4L antibody, Secreted protein G26 antibody, SIS gamma antibody, SIS-gamma antibody, Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody, Small inducible cytokine A4 antibody, Small-inducible cytokine A4 antibody, T cell activation protein 2 antibody, T-cell activation protein 2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived human CCL4 recombinant protein (Position: A24-N92). Human CCL4 shares 76.8% and 79.7% amino acid (aa) sequence identity with mouse and rat CCL4, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.