CCN1 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). And it is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Description:
Rabbit IgG polyclonal antibody for Protein CYR61 (CYR61) detection. Tested with WB in Human, Rat.

Synonyms:
3CH61 antibody, CCN 1 antibody, CCN family member 1 antibody, CCN1 antibody, CCN1 antibody, CYR 61 antibody, Cyr61 antibody, CYR61 protein antibody, CYR61 protein precursor antibody, CYR61 protein precursor antibody, CYR61_HUMAN antibody, Cysteine rich angiogenic inducer 61 antibody, Cysteine rich angiogenic inducer 61 antibody, Cysteine rich angiogenic inducer 61 antibody, Cysteine rich heparin binding protein 61 antibody, Cysteine-rich angiogenic inducer 61 antibody, GIG 1 antibody, GIG1 antibody, GIG1 protein antibody, GIG1 protein antibody, IBP-10 antibody, IGF-binding protein 10 antibody, Igfbp 10 antibody, IGFBP-10 antibody, IGFBP10 antibody, IGFBP10 antibody, Insulin like growth factor binding protein 10 antibody, Insulin like growth factor binding protein 10 antibody, Insulin like growth factor binding protein 10 antibody, Insulin-like growth factor-binding protein 10 antibody, Protein CYR61 antibody, Protein GIG1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CCN1 recombinant protein (Position: K54-D381). Human CCN1 shares 91.8% and 92.1% amino acid (aa) sequence identity with mouse and rat CCN1, respectively.E.coli-derived human CCN1 recombinant protein (Position: K54-D381). Human CCN1 shares 91.8% and 92.1% amino acid (aa) sequence identity with mouse and rat CCN1, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.