CCNF polyclonal (Center), anti-human, mouse

CCNF polyclonal (Center), anti-human, mouse

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In stock
SKU
AC-AP18322c
Catalog Number: AC-AP18322c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24427
Applications: WB
Datasheet

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Background:
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.

Other Names:
Cyclin-F, F-box only protein 1, CCNF, FBX1, FBXO1

Target/Specificity:
This CCNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-524 amino acids from the Central region of human CCNF.

Antigen Region:
496-524

Antigen Type: Synthetic Peptide

Gene Name: CCNF
Gene ID: 899
Primary Accession: P41002
NCBI Accession: NP_001752.2
Other Accession: NP_001752.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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